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    DOI 10.4067/s0718-22442017000200005
    A novel handwritten map of Ultima Esperanza sound (1895) Un novedoso mapa manuscrito del seno de última Esperanza (1895)
    2017-12-01
    Mateo Martinic, B.
    A handwritten map of the eastern maritime zone of the última Esperanza fjord, Region of Magallanes and Chilean Antarctic (Chile), is communicated. Developed by the settler Hermann Eberhard in 1895, its characteristics and appreciations as the first modern map of the district and, as such, the bases for the development of subsequent territorial cartography are described.
    Scopus© Citations 1  4
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    Publicación
    DOI 10.4067/s0718-22442017000200299
    Scopus© Citations 1
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    Publicación
    DOI 10.4067/s0717-95532017000300077
    Psychometric properties of the questionnaire for needs of family members of patients hospitalized in critical units, abbreviated version Propiedades psicométricas del cuestionario de necesidades de familiares de pacientes hospitalizados en unidades críticas, versión abreviada
    2017-12-01
    Villalobos Aburto, Lidia Romina
    ;
    Osorio Spuler, Ximena Odette
    ;
    Valdebenito Santana, José Luis
    The admission of a patient to the Intensive Care Unit has an effect on its inner family circle, the access to information and an empathic treatment being some of the needs of the relatives of the patient in this unit. The short version of the Critical Care Family Needs Inventory (CCFNI) allows to evaluate the satisfaction of those needs by the relatives of the patients in this units and it is considered a useful tool to obtain an overview of this group. Objective: To describe the cultural adaptations and to evaluate the psychometric properties of the short version of the CCFNI in hospitalized patients' relatives in Dr. Hernán Henríquez Aravena's Hospital, Temuco, Chile. Method: This research uses a cross-sectional survey design. The tool was first culturally adapted and then applied to 77 relatives during the time span of five months, after a written consent was provided. Validity of the construct and reliability of the tool are determined. Results: Items 11 and 14 were excluded. The exploratory factorial analysis showed four components whose Alphas of Cronbach were 0.7; 0.7; 0.6 and 0.3. Conclusion: The translation and adapted version applied must continue its psychometric study incorporating a bigger number of relatives of hospitalized patients to confirm the exclusion of items and to check its multidimensional structure. This instrument is a tool to value the needs of relatives of patients hospitalized in Critical Units.
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    Publicación
    DOI 10.4067/s0718-22442017000200255
    HUNTER-GATHERER HEARTHS FROM THE NORTH OF TIERRA DEL FUEGO DURING THE LATE HOLOCENE: CONTEXTS AND ANTHRACOLOGY
    2017
    Massone, Mauricio
    ;
    Eugenia Solari, Maria
    Contextual information from five archaeological sites and its hearths are evaluated. They are located in Marazzi and Tres Arroyos localities, within the valley of glacial origin that connects Inutil and San Sebastian bay, from the north of Tierra del Fuego. Anthracological analysis done on the basis of charcoal from these hearths linked to selk'nam affiliation and their predecessors are evaluated. The chronological range is between approximately 1.218 and 93 years cal. BP. An interpretation of these records is presented.
    Scopus© Citations 6  2  2
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    Publicación
    DOI 10.4067/s0717-73562017005000112
    ASSESSMENT OF AN EAST-WEST PHENOTYPIC VARIATION IN BODY HEIGHT, BODY FORM AND BODY MASS AMONG PREHISTORIC HUNTER-GATHERERS OF PATAGONIA AND TIERRA DEL FUEGO, CHILE
    2017
    Alfonso-Durruty, Marta
    ;
    Giles, Bretton T.
    ;
    San Roman, Manuel
    ;
    Morello, Flavia
    Fuego-Patagonia's marine and terrestrial groups were historically described as phenotypically distinct but, studies of these phenotypic differences have yet to be conducted. This study evaluates phenotypic variation in Fuego-Patagonia. Phenotypic disparities result from extrinsic and intrinsic factors and therefore can reveal differences in both long and short term adaptations as well as genetic differences. Fifty-one adults were assessed. A total of six post-cranial measurements were included: maximum length of the humerus (MHL); maximum length of the radius (MRL); Bicondylar length of the femur (BFL); Maximum length of the tibia (MTL); bi-iliac breadth (BIB), and; antero-posterior diameter of the femoral head (FHD). Brachial index, crural index, body mass, body mass index and stature were then calculated. In general, terrestrial individuals had longer lower limb bones and were the tallest and heaviest. Marine individuals had the shortest bones and were shorter and lighter. Mixed-economy individuals showed mostly intermediate values. The trends are more marked in males than in females. The results suggests the presence of an east-to-west phenotypic gradient in the region that may have resulted from intrinsic and/or extrinsic differences between the groups. But, the sample size of this study is small, and thus the results should be cautiously considered.
    Scopus© Citations 8  2
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    Publicación
    DOI 10.1101/2025.02.09.637306
    REDACTED
    2025-02-10
    Nicole Soto-García
    ;
    David Medina-Ortiz
    ;
    Diego Álvarez-Saravia
    ;
    Diego Sandoval-Vargas
    ;
    Jacqueline Aldridge
    ;
    Sebastián Rodríguez
    ;
    Bárbara A. Andrews
    ;
    Juan A. Asenjo
    ;
    Anamaria Sanchez–Daza
    Plastic pollution presents a critical environmental challenge, necessitating innovative and sustainable solutions. In this context, biodegradation using microorganisms and enzymes offers an environmentally friendly alternative. This work introduces an AI-driven framework that integrates machine learning (ML) and generative models to accelerate the discovery and design of plastic-degrading enzymes. By leveraging pre-trained protein language models and curated datasets, we developed seven ML-based binary classification models to identify enzymes targeting specific plastic substrates, achieving an average accuracy of 89%. The framework was applied to over 6,000 enzyme sequences from the RemeDB to classify enzymes targeting diverse plastics, including PET, PLA, and Nylon. Besides, generative learning strategies combined with trained classification models in this work were applied for de novo generation of PET-degrading enzymes. Structural bioinformatics validated potential candidates through in-silico analysis, highlighting differences in physicochemical properties between generated and experimentally validated enzymes. Moreover, generated sequences exhibited lower molecular weights and higher aliphatic indices, features that may enhance interactions with hydrophobic plastic substrates. These findings highlight the utility of AI-based approaches in enzyme discovery, providing a scalable and efficient tool for addressing plastic pollution. Future work will focus on experimental validation of promising candidates and further refinement of generative strategies to optimize enzymatic performance.
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    Publicación
    DOI 10.32641/andespediatr.v93i3.3636
    Caracterización funcional de pacientes con parálisis cerebral que viven en la región de Magallanes y la Antártica Chilena
    2022-6
    Barria Aburto, Patricio
    ;
    Barria Ruiz, Vanessa
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    Castillo Aguilar, Matías
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    Aguilar Cardenas, Rolando Nemecio
    ;
    Andrade Gallardo, Asterio
    ;
    Nuñez Espinosa, Cristian Andrés
    Resumen: Objetivo: Caracterizar funcionalmente a pacientes con Parálisis Cerebral (PC) que viven en la región de Magallanes y la Antártica Chilena. Pacientes y Método: Estudio observacional descriptivo-retros- pectivo de pacientes con parálisis cerebral, registrados en el Programa de Rehabilitación Ambulatorio de la Corporación de Rehabilitación Club de Leones Cruz del Sur de Punta Arenas entre los años 1986 y 2018. Los pacientes con PC se categorizaron clínicamente, y posteriormente se caracterizaron funcionalmente en base a sistemas de clasificación de habilidades motoras (escala GMFCS), ma nuales (escala MACS), alimentación (escala EDACS) y comunicación (escala CFCS). Resultados: Se incluyeron 106 pacientes con PC. En relación con la clasificación clínica, el tipo más común de PC fue la parálisis espástica bilateral, quienes también presentan el mayor porcentaje de compromiso de funcional en cada una de las áreas evaluada, seguido por la parálisis espástica unilateral. Los casos de PC distónica y otros tipos no clasificables presentaron menor frecuencia de casos. En base a la sub- clasificación clínica diagnóstica, la mayor frecuencia detectada fue la diplejia espástica, concentrando el compromiso funcional especialmente en las habilidades manuales y de comunicación de nivel I en comparación a la hemiplejia. En el caso de cuadriplejia, mixta y no clasificable, presentan menor frecuencia de casos, con un mayor compromiso general en las habilidades de alimentación en nivel I. Conclusión: Los resultados observados de la PC en la región de Magallanes y la Antártica Chilena son similares a estudios disponibles en la literatura. La completa evaluación y clasificación de pacientes con PC posibilita una mayor comprensión de la patología para futuros estudios.
    Scopus© Citations 1  11  10
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